MUNCHIES MAY BE JUST WHAT DOCTOR ORDERS: RESEARCHERS

TORONTO -- Will marijuana-induced munchies help people with HIV and AIDS
combat nausea and avoid the weight-loss that the disease brings on?
Researchers in Toronto are hoping to find out. Canada's first
government-sponsored trial of medicinal marijuana in HIV/AIDS officially
started yesterday, led by researchers from St. Michael's Hospital and the
Community Research Initiative of Toronto.

"I think the time is right to look at this," said principal investigator
Dr. Kevin Gough, medical director of HIV services at the hospital.

"Let's find out what role, if any, that smoked cannabis has in, not only
HIV and AIDS, but other medical illnesses as well."

Advocates of medicinal marijuana believe the drug can be useful for a wide
range of conditions. Anecdotal evidence suggests it helps in pain control,
curbs nausea brought on by chemotherapy or HIV/AIDS drugs, and stimulates
the appetite of people who have lost interest in eating as a result of
their conditions or medications.

But anecdotal evidence doesn't cut it when you are asking a government to
allow large numbers of ill people to buy and smoke what is still an illegal
substance. So Health Canada has authorized research to gather clinical
evidence that may have implications for Canadian policy, and that will
likely be scrutinized by governments outside Canada as well.

The current study is a pilot to gather information that will be used to
design a larger, multi-centre clinical trial. The pilot phase, involving 32
participants with HIV/AIDS, is expected to last about a year.

All participants will have smoked marijuana before. Because there is little
consensus on any risks associated with marijuana use, researchers can't
ethically ask people to take the drug for the first time for a study.

But only people who haven't used the drug in the previous 30 days will be
eligible to take part. That's to ensure there are no lingering effects of
non-study marijuana in their systems.