NEW STUDY SHOWS MARIJUANA MAY FIGHT CANCER

HAMBURG - The active ingredient in marijuana may suppress tumour
invasion in highly invasive cancers, according to new research in Germany.

Cannabinoids, the active components in marijuana, are already used
medically to reduce the side effects of cancer treatment, such as
pain, weight loss and vomiting.

But the new study, published in the latest issue of the Journal of
the National Cancer Institute, finds that the compounds may also have
an anti-cancer effect.

However, more research is needed to determine whether the laboratory
results would hold true in humans, the authors wrote.

Dr Robert Ramer and Dr Burkhard Hinz of the University of Rostock in
Germany investigated whether and by what mechanism cannabinoids
inhibit tumour cell invasion.

Cannabinoids did suppress tumour cell invasion and stimulated the
expression of TIMP-1, an inhibitor of a group of enzymes that are
involved in tumour cell invasion.

"To our knowledge, this is the first report of TIMP-1-dependent
anti-invasive effects of cannabinoids," the two researchers said in a
joint statement.

"This signalling pathway may play an important role in the anti-
metastatic action of cannabinoids, whose potential therapeutic
benefit in the treatment of highly invasive cancers should be
addressed in clinical trials," the authors said.