MARIJUANA: NO SIMPLE ANSWERS

Doctors can't agree on whether patients with cancer, HIV, glaucoma and
other conditions get any benefit from smoking marijuana. Last week, two
studies published in the British Medical Journal found that marijuana isn't
any better for treating pain and nausea than standard drug therapy.

And the U.S. Supreme Court's decision in May to not legalize the
manufacture and sale of pot for medical use only deepens the debate.

Meanwhile, scientists continue to study whether people who smoke pot
strictly for pleasure are endangering their health. In June, researchers at
Boston's Beth Israel Deaconess Medical Center reported that a person's risk
of having a heart attack increases fivefold in the first hour after smoking
marijuana. A fivefold increase doesn't mean much for a young, healthy
person, since the risk of suffering a heart attack is minuscule to begin
with. But for older smokers, and anyone with a condition that increases the
risk for cardiovascular disease (such as diabetes), the study may offer a
reason to think twice before getting high.

Which got me thinking: Are the guys I know who unwind with this illicit
herb putting their health at risk in other ways? For the record, the
majority of pot smokers in this country are men. According to government
figures, adult males are nearly 21/2 times more likely than females to say
they have used marijuana in the last month. Among Americans older than 35,
male pot smokers outnumber female users by even greater numbers.

So, are these guys doing themselves any harm? Several pieces of pot wisdom
about the health of men who smoke marijuana have been handed down over the
years. Back in college, I recall hearing that male pot smokers often
develop gynecomastia, or saggy breasts. Frequent marijuana use is also
rumored to lower a man's sperm count and cause impotence, or erectile
dysfunction.

But none of these claims has ever been proved true in humans, says Dr. Paul
Gahlinger, author of a new book on the history of illegal drugs scheduled
for publication later this year.

Gahlinger notes that exposure to constituents in marijuana seems to slow
sperm in test-tube studies, "but in practice, there doesn't seem to be any
difference at all" in the fertility and sexual potency of men who get high
and men who don't. Likewise, he says, the flabby-chest and impotence
stories lack support too.

In regard to heart disease, Gahlinger notes that no reliable research shows
pot smokers are any more or less likely than nonusers to have
cardiovascular problems. (The Boston study didn't compare people in the two
groups.) Other illegal drugs carry far more serious health risks, he insists.

"Marijuana is one of the safest drugs ever discovered," Gahlinger says.
"It's safer than aspirin."

But many physicians in this country don't share Gahlinger's mellow view.
"Daily smoking of marijuana causes some of the same consequences as the
smoking of tobacco," says Dr. Donald Tashkin, medical director of the
pulmonary function laboratory at the UCLA School of Medicine, among them
bronchitis, a persistent cough and heavy production of phlegm.

Although even regular pot smokers light up only a few times a day, Tashkin
points out that joints are loosely packed and don't have filters. What's
more, pot users inhale deeply and hold smoke in their lungs far longer than
tobacco users. As a result, smoking a marijuana cigarette exposes the lungs
to three to four times more tar than smoking a butt.

There's little data on lung cancer rates among people who smoke only
marijuana, but Tashkin says that lung biopsies of regular pot users reveal
the presence of pre-cancerous cells.

Last year, a study at UCLA's Jonsson Cancer Center showed that mice
implanted with malignant cells develop tumors faster if they're exposed to
THC. "It appears that the THC in marijuana impairs host defense--the
ability to fight infection and fight cancer," Tashkin says.

He points out the irony that cancer and HIV patients, whose immune systems
need bolstering, are among the loudest voices demanding medical marijuana.
It's also conceivable, he says, that THC's effects could make a healthy pot
smoker more vulnerable to infectious diseases, such as pneumonia.

While researchers try to clear the haze over marijuana's impact on health,
a few things aren't up for debate. Driving while high is a terrible idea.
"Don't do it," says Gahlinger. "You're intoxicated."

One study found that airline pilots operating flight simulators still had
delayed reactions 24 hours after smoking pot. Furthermore, like it or not,
the stuff is illegal. Getting busted for possession or fired for flunking a
drug test are guaranteed ways to complicate your life.

Finally, no pot smoker on the planet would deny the existence of a
phenomenon universally known as the munchies. Another study published in
June, by researchers at the State University of New York at Buffalo, found
that marijuana users eat more salty snacks and cheese than nonusers. They
also eat fewer fruits and vegetables, consume greater amounts of beer and
soda, and smoke more cigarettes.

Whatever you think about marijuana, you're kidding yourself if you believe
that the path to better health runs through the chips-and-dip aisle at
7-Eleven.